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Hint : 💡Think about how glucocorticoids act on inflamed synovium.

Correct Answers:

  • Reduces inflammation


Rationale :

🧪Intra-articular hydrocortisone is indicated to decrease synovial inflammation, which is a core driver of pain and swelling in rheumatoid arthritis flares.

🦵By suppressing pro-inflammatory cytokines locally, it reduces joint effusion and improves short-term range of motion.

⏱️The benefit is rapid symptom relief during an acute flare, complementing long-term DMARD therapy that treats disease activity systemically.

🎯Targeted injection limits systemic exposure, focusing the anti-inflammatory effect within the affected joint for quicker functional improvement.

📌Core Message

Local glucocorticoid injection primarily reduces synovial inflammation, providing rapid relief of pain and swelling in an RA flare.

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