Question

After defibrillation and two rounds of epinephrine, the client remains in V-fib. What is the next medication likely to be given?

Answer 1

Correct Answers:

Amiodarone 300 mg IV

Rationale :

⚡Persistent ventricular fibrillation after defibrillation and epinephrine requires an antiarrhythmic medication according to cardiac arrest treatment algorithms.

💉Amiodarone 300 mg IV/IO is the recommended initial dose for refractory V-fib or pulseless ventricular tachycardia after appropriate shocks and epinephrine.

💁‍♂️Amiodarone helps stabilize cardiac electrical activity by prolonging myocardial repolarization and suppressing abnormal ventricular rhythms.

🚑Administration of amiodarone occurs while high-quality CPR and appropriate defibrillation continue during resuscitation.

📌Core Message

Persistent V-fib despite defibrillation and epinephrine requires amiodarone 300 mg IV/IO while resuscitation continues.

Answer 2

Correct Answers:

Pharmacokinetics affects how the drug moves through the body, while pharmacodynamics determines how the drug acts on the body.

Rationale :

💊Pharmacokinetics describes what the body does to a drug through absorption, distribution, metabolism, and excretion.

🎯Pharmacodynamics describes what the drug does to the body through receptor interactions and physiological effects.

🔄The movement of a medication through the body therefore belongs to pharmacokinetics, whereas its mechanism and effects belong to pharmacodynamics.

🧬Understanding both pharmacokinetics and pharmacodynamics helps clinicians predict drug concentrations, therapeutic responses, and adverse effects.

📌Core Message

Pharmacokinetics explains drug movement through the body, while pharmacodynamics explains the drug's effects on the body.

Answer 3

Correct Answers:

"I'll store the tablets in a dark container away from heat and light."

Rationale :

🌑Sublingual nitroglycerin is sensitive to light, heat, moisture, and air, which can reduce its potency.

🧴The tablets should remain in their original tightly closed dark glass container to protect the medication from degradation.

🔥Keeping nitroglycerin away from heat and excessive moisture helps preserve its therapeutic effectiveness during an angina episode.

❤️Correct nitroglycerin storage is especially important because the medication must remain potent enough to provide rapid relief of acute anginal pain.

📌Core Message

Sublingual nitroglycerin should be protected from light, heat, moisture, and air in its appropriate dark container.

Answer 4

Correct Answers:

125

Rationale :

💁‍♂️The prescribed IV volume is 1000 mL and the prescribed infusion time is 8 hours.

💧The pump rate is calculated using total volume ÷ total hours.

⏱️Using the prescription, 1000 mL ÷ 8 hours produces a rate of 125 mL/hr.

💪Because the question requests a whole number, the final pump setting remains 125 mL/hr.

📌Core Message

Infusing 1000 mL over 8 hours requires an infusion pump rate of 125 mL/hr.

Answer 5

Correct Answers:

13

Rationale :

⚖️The required dopamine dose is calculated from 5 mcg/kg/min × 70 kg, producing 350 mcg/min.

⏰Converting the dose to an hourly amount gives 350 mcg/min × 60 minutes, producing 21,000 mcg/hr or 21 mg/hr.

💉The available concentration is calculated using 400 mg ÷ 250 mL, producing 1.6 mg/mL.

🤦‍♂️The pump rate is therefore 21 mg/hr ÷ 1.6 mg/mL, producing 13.125 mL/hr, which rounds to 13 mL/hr.

📌Core Message

A 70-kg patient receiving dopamine at 5 mcg/kg/min from a concentration of 400 mg in 250 mL requires approximately 13 mL/hr.

Answer 6

Correct Answers:

SABA then ICS

Rationale :

🌬️Albuterol, a short-acting beta₂ agonist, rapidly produces bronchodilation by relaxing bronchial smooth muscle.

💁‍♂️Using the bronchodilator first opens narrowed airways and improves airflow through the respiratory tract.

💨Once the airways are more open, inhaled fluticasone can penetrate more effectively into the lungs to provide its anti-inflammatory effect.

🧴The client should also rinse the mouth after fluticasone to reduce the risk of oral candidiasis associated with inhaled corticosteroids.

📌Core Message

Administer the short-acting bronchodilator first, followed by the inhaled corticosteroid, to optimize medication delivery to the airways.

Answer 7

Correct Answers:

"This medication may mask signs of low blood sugar, so monitor your glucose closely."

Rationale :

🩸Beta blockers such as metoprolol can suppress adrenergic manifestations of hypoglycemia, particularly tachycardia and tremors.

💓A client who usually recognizes low glucose through a rapid heartbeat or shakiness may therefore have less warning after beginning metoprolol.

💁‍♂️Frequent blood glucose monitoring becomes especially important because objective glucose readings can identify hypoglycemia despite reduced symptoms.

🧠Some manifestations such as sweating or neuroglycopenic symptoms may still occur, so the client should remain alert for other signs of declining glucose.

📌Core Message

Metoprolol can mask important adrenergic signs of hypoglycemia, making close blood glucose monitoring especially important.

Answer 8

Correct Answers:

"You should avoid consuming grapefruit or grapefruit juice while taking atorvastatin."

Rationale :

🍊Grapefruit can inhibit intestinal CYP3A4, an enzyme involved in the metabolism of atorvastatin.

💊Reduced atorvastatin metabolism can increase medication concentrations and raise the risk of dose-related adverse effects.

💪Higher statin exposure can increase the risk of myopathy and rhabdomyolysis, particularly with substantial grapefruit consumption.

⚠️Teaching the client to avoid or limit grapefruit products according to prescribed medication guidance promotes safer atorvastatin therapy.

📌Core Message

Grapefruit can increase atorvastatin exposure through CYP3A4 inhibition, increasing the potential for serious muscle toxicity.

Answer 9

Correct Answers:

Hold the medication and assess for rhabdomyolysis.

Rationale :

🚨The combination of muscle pain and dark urine in a client taking atorvastatin strongly suggests possible rhabdomyolysis.

💪Statins can rarely cause severe skeletal muscle breakdown, releasing myoglobin into the bloodstream.

👉Myoglobin can damage the kidneys and lead to acute kidney injury, making rapid recognition and intervention essential.

🩺The nurse should hold atorvastatin, notify the provider, and anticipate assessment of markers such as creatine kinase and renal function.

📌Core Message

Muscle pain with dark urine during atorvastatin therapy is a warning sign of rhabdomyolysis requiring immediate evaluation and withholding the medication.

Answer 10

Correct Answers:

Metoprolol and amlodipine

Rationale :

🐢Metoprolol decreases heart rate by blocking beta₁-adrenergic receptors in the heart and reducing sinoatrial node activity.

💊Amlodipine primarily causes peripheral vasodilation, but when combined with a medication that lowers heart rate, careful monitoring for bradycardia and hypotension is warranted.

💁‍♂️Among the listed medication combinations, metoprolol-containing therapy creates the greatest concern for clinically significant slowing of the pulse because beta blockade directly reduces cardiac rate.

📉Clients receiving such cardiovascular therapy should have heart rate and blood pressure monitored for excessive cardiovascular depression.

📌Core Message

The combination containing metoprolol presents the greatest listed risk for significant bradycardia because beta₁ blockade directly slows the heart rate.

Pharmacology - Compu-Med Vocational 2026

No.

1 :
After defibrillation and two rounds of epinephrine, the client remains in V-fib. What is the next medication likely to be given?

2 :
Which statement best summarizes the relationship between pharmacodynamics and pharmacokinetics?

3 :
A nurse is teaching a client about the proper storage of sublingual nitroglycerin. Which statement indicates understanding?

4 :
A provider prescribes 0.9% normal saline (NS) 1000 mL IV to infuse over 8 hours using an infusion pump. What is the correct infusion rate in mL/hr? (Record your answer as a whole number.)

6 :
A patient with asthma is prescribed albuterol (SABA) and fluticasone (ICS). What is the correct order?

8 :
A nurse is educating a client who is prescribed atorvastatin for hyperlipidemia. Which of the following should the nurse teach the client regarding grapefruit consumption?

9 :
A patient on atorvastatin reports muscle pain and dark urine. What is the nurse's best action?

10 :
Which combination of medications would put a client at greatest risk for severe bradycardia?

Pharmacology - Compu-Med Vocational 2026

No.

1 : After defibrillation and two rounds of epinephrine, the client remains in V-fib. What is the next medication likely to be given?

2 : Which statement best summarizes the relationship between pharmacodynamics and pharmacokinetics?

3 : A nurse is teaching a client about the proper storage of sublingual nitroglycerin. Which statement indicates understanding?

4 : A provider prescribes 0.9% normal saline (NS) 1000 mL IV to infuse over 8 hours using an infusion pump. What is the correct infusion rate in mL/hr? (Record your answer as a whole number.)

6 : A patient with asthma is prescribed albuterol (SABA) and fluticasone (ICS). What is the correct order?

8 : A nurse is educating a client who is prescribed atorvastatin for hyperlipidemia. Which of the following should the nurse teach the client regarding grapefruit consumption?

9 : A patient on atorvastatin reports muscle pain and dark urine. What is the nurse's best action?

10 : Which combination of medications would put a client at greatest risk for severe bradycardia?

1 :
After defibrillation and two rounds of epinephrine, the client remains in V-fib. What is the next medication likely to be given?

2 :
Which statement best summarizes the relationship between pharmacodynamics and pharmacokinetics?

3 :
A nurse is teaching a client about the proper storage of sublingual nitroglycerin. Which statement indicates understanding?

4 :
A provider prescribes 0.9% normal saline (NS) 1000 mL IV to infuse over 8 hours using an infusion pump. What is the correct infusion rate in mL/hr? (Record your answer as a whole number.)

6 :
A patient with asthma is prescribed albuterol (SABA) and fluticasone (ICS). What is the correct order?

8 :
A nurse is educating a client who is prescribed atorvastatin for hyperlipidemia. Which of the following should the nurse teach the client regarding grapefruit consumption?

9 :
A patient on atorvastatin reports muscle pain and dark urine. What is the nurse's best action?

10 :
Which combination of medications would put a client at greatest risk for severe bradycardia?