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Synergistic effect
💊Meperidine (Demerol) is an opioid analgesic, while promethazine (Phenergan) is an antihistamine with sedative properties.
🌀Together, they produce a synergistic effect, where combined action is greater than either drug alone.
😴Promethazine enhances pain control and sedation, reducing the need for higher opioid doses.
📋This combination is often used to improve comfort and reduce nausea in postoperative patients.
📌Core Message
Combining meperidine and promethazine produces a synergistic effect, enhancing pain relief and sedation.
This question is from NCLEX PN-Readiness Assessment Test-2 which contains 100 questions.
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